Vectors and compounds for direct expression of activated...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/57 (2006.01) C12N 9/64 (2006.01) C12N 15/62 (2006.01) C12Q 1/04 (2006.01)

Patent

CA 1339938

A method for the direct recombinant production of activated protein C is described. DNA compounds, vectors, and transformants useful in the method are also disclosed. The method involves transformation and culture of a host cell with a recombinant DNA vector that encodes a protein C molecule in which the activation peptide is replaced with a cleavage sequence for a cell associated protease.

584921

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