Vectors and compounds for expression of zymogen forms of...

Details Vectors and compounds for expression of zymogen forms of... Vectors and compounds for expression of zymogen forms of...

C - Chemistry, Metallurgy

12

N

195/39.1, 195/1.

C12N 15/57 (2006.01) A61K 38/48 (2006.01) C12N 9/64 (2006.01)

Patent

CA 1340111

A method for the recombinant production of zymogen forms of human protein C is described. These zymogen forms differ from native zymogen protein C in their increased sensitivity to activation by thrombin and thrombin/thrombomodulin. DNA compounds, vectors, and transformants useful in the method are also disclosed.

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