Vectors capable of immortalizing non-dividing cells and...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/63 (2006.01) C12N 5/16 (2006.01) C12N 5/22 (2006.01) C12N 7/01 (2006.01) C12N 15/64 (2006.01) C12N 15/867 (2006.01) C12P 21/00 (2006.01)

Patent

CA 2389667

Vectors capable of stably integrating a transgene in the genome of a non- dividing cell or of a slowly-dividing cell, said vector comprising or expressing at least one immortalization molecule and cells immortalized with said vectors.

La présente invention concerne des vecteurs capables d'intégrer de façon stable un transgène dans le génome d'une cellule ne se divisant pas ou se divisant lentement. En l'occurrence, ce vecteur comprend ou exprime au moins une molécule d'immortalisation. L'invention concerne également des cellules immortalisées au moyen de ces vecteurs.

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