A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/385 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) A61P 29/00 (2006.01) A61P 31/00 (2006.01) A61P 33/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2422603
The invention relates to a novel use of a Bordetella adenylcyclase toxin in the manufacturing of vectors for targeting in vivo a molecule of interest, specifically to CD11b expressing cells. The invention also relates to an immunogenic composition that primes immune responses, to pharmaceutical compositions and to a new vector for molecule delivery to CD11b expressing cells.
Cette invention concerne un emploi nouveau de la toxine adénylcyclase <i>Bordetella</i> dans l'obtention de vecteurs permettant de cibler <i>in vivo</i> une molécule d'intérêt, spécifiquement des cellules exprimant CD11b. L'invention concerne également une composition immunogène qui amorce une réponse immunitaire, des compositions pharmaceutiques et un nouveau vecteur pour le transport de molécules vers des cellules exprimant CD11b.
Bauche Cecile
El-Azami El-Idrissi Mohammed
Fayolle Catherine
Guermonprez Pierre
Guiso Nicole
Centre National de La Recherche Scientifique
Institut Pasteur
Robic
LandOfFree
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