Vectors having both isoforms of b-hexosaminidase

Details Vectors having both isoforms of b-hexosaminidase Vectors having both isoforms of b-hexosaminidase

C - Chemistry, Metallurgy

12

N

C12N 15/56 (2006.01) A01H 5/02 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 35/14 (2006.01) A61K 38/47 (2006.01) A61K 48/00 (2006.01) C12N 5/00 (2006.01) C12N 5/02 (2006.01) C12N 9/24 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01) C12N 15/74 (2006.01) C12N 15/85 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2483915

Disclosed are compositions and methods related to nucleic acid constructs containing a HexB encoding element and a HexA encoding element. These constructs can be used in the treatment of Tray-Sachs and Sandoff disease.

L'invention concerne des compositions et des proc~d~s relatifs ~ des construction d'acide nucl~ique contenant un ~l~ment codant pour HexB et un ~l~ment codant pour HexA. Ces constructions peuvent Útre utilis~es dans le traitement des maladies de Tay-Sachs et de Sandoff.

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