Vectors having both isoforms of beta-hexosaminidase and uses...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 35/14 (2006.01) C12N 15/00 (2006.01) C12N 15/87 (2006.01) C12N 9/24 (2006.01) C12N 15/02 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2557595

Disclosed are compositions and methods related to nucleic acid constructs containing a HexB encoding element and a HexA encoding element. These constructs can be used in the treatment of Tay-Sachs and Sandoff disease.

L'invention concerne des compositions et des procédés concernant des constructions d'acides nucléiques qui renferment un élément de codage HexB et un élément de codage HexA. Ces constructions peuvent être utilisées pour le traitement des maladies de Tay-Sachs et Sandoff.

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