Vegf antagonist formulations

Details Vegf antagonist formulations Vegf antagonist formulations

A - Human Necessities

61

K

A61K 38/17 (2006.01) A61K 47/00 (2006.01)

Patent

CA 2598711

Formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided including a pre-lyophilized formulation, a reconstituted lyophilized formulation, and a stable liquid formulation. Preferably, the fusion protein has the sequence of SEQ ID NO:4.

La présente invention concerne des formulations d'un antagoniste de protéine de fusion spécifique du facteur de croissance endothéliale vasculaire (vascular endothelial growth factor / VEGF), comprenant une formulation pré-lyophilisée, une formulation lyophilisée reconstituée, et une formulation liquide stable. La protéine de fusion a de préférence la séquence SEQ ID NO:4.

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