Vegf inhibitors for the treatment of malignant pleural effusion

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A61K 38/18 (2006.01) A61P 11/00 (2006.01) A61P 35/00 (2006.01) C07K 14/71 (2006.01)

Patent

CA 2568534

Methods for treating a human patient suffering from malignant pleural effusion by administering an effective amount of a vascular endothelial growth factor (VEGF) inhibitor to the human patient. The VEGF inhibitor is a VEGF trap protein comprising a dimeric protein having two fusion polypeptides having the sequence of SEQ ID NO:2.

Méthode de traitement d'un patient souffrant d'un épanchement pleural malin, qui consiste à administer à ce patient une dose efficace d'un inhibiteur du facteur de croissance de l'endothélium vasculaire (VEGF). L'inhibiteur VEGF est une protéine de piégeage comprenant une protéine dimère à deux polypeptides de fusion à séquence SEQ ID NO:2.

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