Vegf traps and therapeutic uses thereof

Details Vegf traps and therapeutic uses thereof Vegf traps and therapeutic uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) C07K 14/71 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01)

Patent

CA 2529660

Nucleic acid molecules and multimeric proteins capable of binding vascular endothelial growth factor (VEGF). VEGF traps are disclosed which are therapeutically useful for treating VEGF-associated conditions and diseases, and are specifically designed for local administration to specific organs, tissues, and/or cells.

Molécules d'acide nucléique et protéines multimères capables de se lier au facteur de croissance endothéliale vasculaire (VEGF). La présente invention concerne des pièges de VEGF qui sont thérapeutiquement utiles pour traiter des états pathologiques ou maladies associés à VEGF. Lesdits pièges de VEGF sont spécifiquement conçus pour l'administration locale à des organes, tissus et / ou cellules spécifiques.

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