A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 9/50 (2006.01)
Patent
CA 2520020
This invention provides coated pellets comprising a) a pellet core which comprises venlafaxine hydrochloride; b) a first coating which comprises a lipophilic layer or a sparingly water-soluble layer, and c) a second coating which comprises a water-insoluble polymer or polymer mixture. In another aspect this invention provides compositions which comprises the coated pellets. In a further aspect, the invention provides a process for preparing the coated pellets which process avoids use of organic solvents at least for the second coating.
La présente invention a trait à des comprimés enrobés comprenant a) un noyau de comprimé comportant du chlorhydrate de venlafaxine, b) un premier enrobage comportant une couche lipophile ou une couche peu hydrosoluble, et c) un deuxième enrobage comportant un polymère ou un mélange à base de polymère non hydro-insoluble. La présente invention a également trait à des compositions comportant les comprimés enrobés. L'invention a trait en outre à un procédé pour la préparation de comprimés enrobés, lequel procédé évite l'utilisation de solvants organiques au moins pour le deuxième enrobage.
Doshi Chetan
Gopinathan Dinesh
Kulkarni Sushrut
Sukthankar Mangesh
Thakker Prashant
Fetherstonhaugh & Co.
Sandoz Ag
LandOfFree
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