A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
128/104, 167/251
A61K 9/22 (2006.01) A61K 9/00 (2006.01) A61K 31/275 (2006.01)
Patent
CA 1261703
ABSTRACT The invention relates to a dosage form for delivering the beneficial drug verapamil to a biological environment of use, the dosage form comprising: (a) a wall comprising in at least a part a composition comprising a cellulose acylate, which wall is permeable to the passage of fluid, impermeable to the passage of verapamil, and surrounds and forms: (b) a compartment; (c) a dosage amount of verapamil in the compartment, with the proviso that said verapamil is present with mannitol in the compartment in a nonequilibrium ratio of 0.9 to 1.1; and, (d) at least one passageway in the wall connecting the compartment with the exterior of the dosage form for dispensing verapamil to the environment of use over time.
532296
Hamel Lawrence G.
Magruder Paul
Stephens Sally I.
Wong Patrick S.l.
Alza Corporation
Smart & Biggar
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