Verapamil dosage form

Details Verapamil dosage form Verapamil dosage form

A - Human Necessities

61

K

128/104, 167/251

A61K 9/22 (2006.01) A61K 9/00 (2006.01) A61K 31/275 (2006.01)

Patent

CA 1261703

ABSTRACT The invention relates to a dosage form for delivering the beneficial drug verapamil to a biological environment of use, the dosage form comprising: (a) a wall comprising in at least a part a composition comprising a cellulose acylate, which wall is permeable to the passage of fluid, impermeable to the passage of verapamil, and surrounds and forms: (b) a compartment; (c) a dosage amount of verapamil in the compartment, with the proviso that said verapamil is present with mannitol in the compartment in a nonequilibrium ratio of 0.9 to 1.1; and, (d) at least one passageway in the wall connecting the compartment with the exterior of the dosage form for dispensing verapamil to the environment of use over time.

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