Versatile precursors for annonaceous acetogenins

Details Versatile precursors for annonaceous acetogenins Versatile precursors for annonaceous acetogenins

C - Chemistry, Metallurgy

07

D

C07D 407/04 (2006.01) C07D 307/12 (2006.01)

Patent

CA 2350254

A tetrahydrofuran (THF) epoxide and method of its preparation according to a novel stereoselective synthetic method. The compounds of the invention are used to prepare therapeutically active mono-THF and bis-THF containing Annonaceous Acetogenins.

Tétrahydrofurane (THF) époxydique et son procédé de préparation selon un nouveau procédé synthétique stéréosélectif. Les composés selon l'invention sont utilisés dans la préparation d'acétogénines d'annonacées thérapeutiquement actives contenant mono-THF et de bis-THF.

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