Veterinary aqueous injectable suspensions containing...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/165 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2532755

This invention relates to pharmaceutical compositions for veterinary use in form of aqueous injectable suspensions comprising Florfenicol or Florfenicol in form of a substantially water-insoluble complex, co-crystal or salt, sterile and micronised, in a concentration up to 500 mg/ml. The suspensions enable parenteral antimicrobial therapies in animals, with limited numbers of injections and showing good general- and local tolerances. They also possess a limited sedimentation on standing as well as after shipping, are easily resuspendable and have good syringablity.

L'invention concerne des compositions pharmaceutiques utilisées dans le domaine vétérinaire sous forme de suspensions aqueuses injectables contenant du Florfenicol ou du Florfenicol sous forme de complexe, de co-cristal ou de sel sensiblement insoluble dans l'eau, stérile et microfin, dans une concentration pouvant atteindre 500 mg/ml. Ces suspensions permettent de procéder à des traitements thérapeutiques antimicrobiens par voie parentérale chez les animaux, avec des quantités limitées d'injections, et présentent de bonnes tolérances à un niveau général et local. Lesdites suspensions présentent également une sédimentation limitée à la verticale, ainsi qu'après leur transport, et possèdent une bonne capacité de resuspension, et d'injection à l'aide d'une seringue.

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