Veterinary composition against endoparasites and process for...

A - Human Necessities – 61 – K

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A61K 31/415 (2006.01) A01N 53/00 (2006.01) A61K 31/215 (2006.01) A61K 31/275 (2006.01) A61K 31/34 (2006.01) A61K 31/40 (2006.01) A61K 31/425 (2006.01)

Patent

CA 1332810

The invention relates to veterinary compositions suitable against endoparasites containing as active ingredient at least one pyrethroid derivative of the general formula I Image /I/ - wherein R and R1 represent a C1-4 alkyl group or halogen atom, Z represents a group of the general formula a) or b) or c) Image (a) Image (b) Image (c) or the isomeric mixture thereof in whatever ratio and optionally a benzimidazole derivative of the general formula II Image /II/ or an aniline derivative of the general formula III Image /III/ - wherein Y represents -O-, -S-, -NH-, -CO-, -SO-, -SO2- or a valence line, R4 represents hydrogen atom, C1-4 alkyl group or C2-5 alkoxycarbonyl group or phenyl group, R5 stands for a group of the general formula -NH-COOR9 or 4-thiazolyl group, R6 stands for hydrogen atom, C1-4 -S-alkyl or -S-phenyl group, R7 stands for -NO2 or -NHR10 group, R8 stands for a group of the general formula -CSNHCOOR11 or -C(NR12)NHCOOR13 or -COCH2OR14, in an amount of 0.5-50 weight%, while optionally the ratio of the active ingredients of the general formulae I and II or III is 1:7-1:1, in addition to the filling, diluting and other auxiliary agents generally used in veterinary therapeutics. The invention relates, furthermore, to a process for the preparation thereof.

607746

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