Vigor enhancement via administration of pyrimidine derivatives

Details Vigor enhancement via administration of pyrimidine derivatives Vigor enhancement via administration of pyrimidine derivatives

A - Human Necessities

61

K

A61K 31/519 (2006.01) A61P 19/08 (2006.01) A61P 25/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2670341

Disclosed herein are methods for increasing the overall vigor of a subject, and/or vigor of target tissues of a subject. Exemplified herein is the utilization of pyrimidine derivatives which act to stimulate stem cell proliferation. In addition to increasing vigor, such stem cell proliferation agents (SCPA) may be used to enhance and/or improve the outcome of other therapies, and may be used in psychiatric applications. Increasing vigor in subjects is not necessarily targeted to the treatment of a disease, thus, the methods can include administration to clinically healthy animals.

L'invention concerne des procédés d'amélioration de la vigueur globale d'un sujet et/ou de la vigueur de tissus cibles d'un sujet. L'utilisation de dérivés de pyrimidine qui agissent en stimulant la prolifération de cellules souches est donnée en exemple ici. En plus d'augmenter la vigueur, de tels agents de prolifération de cellules souches (SCPA) peuvent être utilisés pour augmenter et/ou améliorer le résultat d'autres thérapies et peuvent être utilisés pour des applications psychiatriques. L'augmentation de la vigueur chez des sujets n'est pas nécessairement ciblée au traitement d'une maladie. Les procédés peuvent ainsi inclure l'administration à des animaux cliniquement sains.

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