C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/85 (2006.01) A01K 67/027 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C12N 15/11 (2006.01) C12N 15/12 (2006.01)
Patent
CA 2054149
VILLIN GENE PROMOTER SEQUENCE AND ITS USE IN VECTORS, TRANSFORMED MAMMALIAN CELL LINES, TRANSGENIC ANIMALS, AND CELL LINES DERIVED FROM THE ANIMALS Abstract An isolated DNA sequence encoding a promoter of the human villin gene is provided. The DNA sequence can be operatively linked to a nucleotide sequence of a gene, such as an oncogene, and incorporated in cloning and expression vectors. The vectors are useful in the production of transgenic, non-human mammals as models of colorectal cancer.
Babinet Charles
Huet Christian
Louvard Daniel
Pringault Eric
Robine Sylvie
Institut Nationale de La Sante Et de La Recherche Medicale
Institut Pasteur
Mckay-Carey & Company
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