Vinca derivative conjugates containing a c-3 detergent chain

Details Vinca derivative conjugates containing a c-3 detergent chain Vinca derivative conjugates containing a c-3 detergent chain

C - Chemistry, Metallurgy

07

K

530/15

C07K 16/30 (2006.01) A61K 47/48 (2006.01) C07D 519/04 (2006.01) C07K 2/00 (2006.01) C07K 14/765 (2006.01)

Patent

CA 1336119

La présente invention a pour objet des conju- gués de dérivé de vinca (indole-dihydroindole comportant en position C-3 une chaîne détergente d'au moins 7 atomes de carbone aliphatique liée par un lien covalent à un transporteur macromoléculaire de nature polypeptidique, ainsi que des compositions pharmaceutiques en comprenant et un procédé de préparation.

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