C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/271.3
C07D 471/16 (2006.01) C07C 45/51 (2006.01) C07C 47/14 (2006.01) C07D 209/16 (2006.01) C07D 209/48 (2006.01) C07D 471/04 (2006.01) C07D 471/20 (2006.01)
Patent
CA 1137478
Abstract of the Disclosure: The preparation of vincadifformine and some derivatives thereof for use as a starting material for synthesis of the corresponding vincamine derivatives or for synthesis of bisindole alkaloids having clinically important antitumor properties is described. A .alpha.-methyl tetrahydro .beta.-carboline and a functionnalised aldehyde are condensed to provide in one step the corresponding vincadifformine.
338591
Hirons & Rogers
Omnium Chimique S.a.
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