Vinyl-phenyl derivatives for inflammation and immune-related...

Details Vinyl-phenyl derivatives for inflammation and immune-related... Vinyl-phenyl derivatives for inflammation and immune-related...

C - Chemistry, Metallurgy

07

D

C07D 417/04 (2006.01) A61K 31/166 (2006.01) A61K 31/44 (2006.01) A61K 31/455 (2006.01) A61P 37/06 (2006.01) A61P 37/08 (2006.01) C07C 233/65 (2006.01) C07C 233/75 (2006.01) C07D 211/70 (2006.01) C07D 213/81 (2006.01) C07D 223/04 (2006.01) C07D 263/32 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 413/04 (2006.01)

Patent

CA 2640091

The invention relates to compounds of structural formula (Ia): Formula (Ia) or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein X1, X2, X3, X4, X6, X10, R1 , Y, Z, L, and n are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.

L'invention concerne des composés de formule structurelle (Ia) ou un sel pharmacocompatible, un solvate, un clathrate ou un promédicament correspondant. Dans cette formule, X1, X2, X3, X4, X6, X10, R1 , Y, Z, L, et n sont tels que définis ci-après. Ces composés sont utilisés en tant qu'agents immunosuppresseurs et pour traiter et prévenir des troubles inflammatoires, allergiques et immuns.

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