Vinylogous acids derivatives as chymase inhibitors

Details Vinylogous acids derivatives as chymase inhibitors Vinylogous acids derivatives as chymase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 209/12 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2665046

The invention is concerned with novel vinylogous acid derivatives of formula (I) wherein A and R1 to R5 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit chymase and can be used as medicaments.

L'invention concerne de nouveaux dérivés d'acides vinylogues représentés par la formule (I) dans laquelle A et R1 à R5 sont tels que définis dans la description et dans les revendications, ainsi que des sels physiologiquement acceptables de ces dérivés. Ces composés inhibent la chymase et peuvent être utilisés comme médicaments.

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