Viral antigen and vaccine against isav (infectious salmon...

Details Viral antigen and vaccine against isav (infectious salmon... Viral antigen and vaccine against isav (infectious salmon...

C - Chemistry, Metallurgy

12

N

C12N 15/44 (2006.01) A61K 38/17 (2006.01) A61K 39/145 (2006.01) A61P 31/14 (2006.01) C07H 21/00 (2006.01) C07K 14/11 (2006.01) C07K 14/47 (2006.01) C12N 15/11 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2402339

Disclosed are isolated Infectious Salmon Anaemia (ISA) antigen polypeptides comprising all or part of the European ISA antigen amino acid sequence shown in Annex II or a variant sequence thereof e.g. as encoded by the nucleotide sequence of Annex I. The polypeptides may be expressed recombinantly and formulated in vaccines against the ISA virus or used in diagnosis or to raise antibodies.

L'invention concerne des polypeptides antigéniques isolés de l'anémie infectieuse du saumon (AIS) comprenant la totalité ou une partie de la séquence d'acides aminés de l'antigène de l'AIS européenne présentée dans l'annexe II ou une forme variante de cette séquence, par exemple celle codée par la séquence nucléotidique présentée dans l'annexe I. Ces polypeptides peuvent être exprimés sous forme recombinée et servir à la préparation de vaccins dirigés contre le virus de l'AIS, ou ils peuvent être utilisés pour l'établissement de diagnostics ou pour stimuler la production d'anticorps.

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