Viral protein binding compositions and methods

Details Viral protein binding compositions and methods Viral protein binding compositions and methods

A - Human Necessities

61

K

A61K 38/16 (2006.01) A61P 31/12 (2006.01) A61P 37/02 (2006.01) C07K 14/03 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2379618

A pharmaceutical composition comprises M3 protein as encoded by virus MHV 68, or a homologue of said M3 protein, for use in binding to a chemokine or a chemokine analogue in vivo, or to block binding of chemokines to correpsonding cell surface receptors in vivo, to produce an immunomodulatory effect, or to blind to a chemokine analgue present in a virus or parasite to block its entry into cells.

L'invention concerne une composition pharmaceutique, qui comprend une protéine M3 encodée par le virus MHV 68, ou un homologue de la protéine M3. Cette composition est utilisée pour réaliser in vivo une liaison à une chimiokine ou à un analogue de la chimiokine ou pour bloquer in vivo la liaison de chimiokines à des récepteurs de surface cellulaire correspondants aux fins de produire un effet immunomodulateur, ou pour réaliser une liaison à un analogue de la chimiokine présent dans un virus ou des parasites aux fins de bloquer la pénétration de ces derniers dans des cellules.

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