Viral reporter particles

Details Viral reporter particles Viral reporter particles

A - Human Necessities

61

K

A61K 39/00 (2006.01) C07K 14/16 (2006.01) C12N 15/62 (2006.01) C12N 15/867 (2006.01)

Patent

CA 2439620

The present invention features a chimeric protein containing a .beta.- lactamase region and either a Vpr region or a Vpx region. The chimeric protein can be packaged into a viral reporter particle, introduced into a cell recognized by the viral particle and provide intracellular .beta.-lactamase activity.

La présente invention concerne une protéine chimérique contenant une région .beta.-lactamase et une région Vpr ou une région Vpx. Cette protéine chimérique peut être intégrée dans une particule rapporteur virale, introduite dans une cellule reconnue par la particule virale, et conférer une activité .beta.-lactamase intracellulaire.

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