Viral vector and its applications

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/86 (2006.01)

Patent

CA 2670163

The viral vector comprises a replicon of the Semiliki Forest Virus (SFV) mutated in the sequence of nucleotides which codes the nsp2 subunit of the SFV replicase. Said viral vector is useful for generating stable cell lines with capacity to constitutively express heterologous products of interest.

Le vecteur viral comprend un réplicon du virus de la forêt de Semliki (SFV) muté au niveau de la séquence de nucléotides codant pour la sous-unité nsp2 de la réplicase du SFV. Ledit vecteur viral peut être utilisé pour la production de lignées cellulaires stables capables d'exprimer consécutivement des produits hétérologues présentant un intérêt.

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