C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A61K 39/12 (2006.01) C07K 14/18 (2006.01) C12N 7/01 (2006.01) C12N 15/869 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2172815
This invention relates to the field of Bovine Viral Diarrhea Virus (BVDV), and vaccines for the treatment thereof. This invention describes the preparation of live, attenuated Bovine Herpesvirus type I (BHV-1) as a virus, vaccine and vector for expression of BVDV antigens. A BVDV cDNA clone containing sequences corresponding to glycoprotein gp53 is inserted into an inactivated BHV-1 virus.
Cette invention se rapporte au virus de la maladie des muqueuses (BVDV) et à des vaccins utilisés dans le traitement de cette maladie. Cette invention concerne la préparation de l'herpèsvirus des bovins vivants atténués, de type 1 (BHV-1), sous forme d'un virus, d'un vaccin et d'un vecteur d'expression des antigènes de BVDV. Un clone d'ADNc du BVDV contenant des séquences correspondant à la glycoprotéine gp53 est inséré dans un virus BHV-1 inactivé.
Haanes Elizabeth J.
Wardley Richard C.
Corporation Bayer
Swabey Ogilvy Renault
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