Virosomes comprising hemagglutinin derived from an influenza...

Details Virosomes comprising hemagglutinin derived from an influenza... Virosomes comprising hemagglutinin derived from an influenza...

A - Human Necessities

61

K

A61K 9/127 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2689960

The present invention relates to virosomes comprising hemagglutinin (HA) with improved fusion activity. Prefer-ably, the HA comprised in said virosomes was derived from influenza virus produced in a cell line. The present invention also relates to compositions and a kit comprising the virosomes according to the invention. Further, the present invention relates to uses and methods involving said virosomes, as well as to a method for preparing same.

La présente invention porte sur des virosomes comprenant l'hémaglutinine (HA) avec une meilleure activité de fusion. De préférence, la HA comprise dans lesdits virosomes a été tirée d'un virus de la grippe produit dans une lignée cellulaire. La présente invention porte également sur des compositions et sur une trousse comprenant les virosomes selon l'invention. En outre, la présente invention porte sur les utilisations et sur des procédés impliquant lesdits virosomes, ainsi que sur un procédé pour les préparer.

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