Virosomes, methods of preparation, and immunogenic compositions

Details Virosomes, methods of preparation, and immunogenic compositions Virosomes, methods of preparation, and immunogenic compositions

C - Chemistry, Metallurgy

12

N

C12N 7/01 (2006.01) A61K 39/12 (2006.01) A61K 39/21 (2006.01) A61P 31/12 (2006.01) A61P 37/04 (2006.01) C12N 7/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) G01N 33/564 (2006.01)

Patent

CA 2657648

Briefly described, virosomes, methods of preparing virosomes, immunogenic compositions that include virosomes, and methods of eliciting an immune response using immunogenic compositions that include virosomes are described herein. A virosome can include at least one viral surface envelope glycoprotein expressed on the surface of the virosome. The virosome can also optionally include at least one adjuvant molecule expressed on the surface of the virosome.

L'invention concerne des virosomes, des procédés de préparation de virosomes, des compositions immunogènes comprenant des virosomes et des procédés de provocation d'une réponse immunitaire en utilisant des compositions immunogènes qui comprennent lesdits virosomes. Un virosome peut comprendre au moins une glycoprotéine d'enveloppe de surface virale, exprimée à la surface du virosome. Le virosome peut également éventuellement comprendre au moins une molécule adjuvante exprimée à la surface du virosome.

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