Virulence-associated nucleic acid sequences and uses thereof

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/00 (2006.01) A61K 49/00 (2006.01) C07K 14/21 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2310561

Disclosed are bacterial virulence polypeptides and nucleic acid sequences (e.g., DNA) encoding such polypeptides, and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides to screen for antibacterial or bacteriostatic compounds

L'invention concerne des polypeptides associés à la virulence bactérienne, des séquences nucléotidiques (par exemple, ADN) codant de tels polypeptides, ainsi que des procédés permettant de produire de tels polypeptides par des techniques de recombinaison. L'invention concerne également des procédés d'utilisation de ces polypeptides dans le but de dépister des composés antibactériens ou bactériostatiques.

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