Virus removal by nanofiltration

Details Virus removal by nanofiltration Virus removal by nanofiltration

C - Chemistry, Metallurgy

07

K

C07K 1/34 (2006.01) A61L 2/00 (2006.01)

Patent

CA 2655897

A method for purifying a protein solution from infective particles comprising (a) adding a macromolecule to the solution; and (b) passing the solution through a nanofilter. The macromolecule may be selected from a polymer of at least 3 monomers of sugars, amino acids, glycols, alcohols, lipids or phospholipids.

L'invention concerne un procédé de purification d'une solution de protéine pour en éliminer les particules infectieuses, comprenant les opérations consistant à (a) ajouter une macromolécule à la solution; et (b) faire passer la solution à travers un nanofiltre. La macromolécule peut être choisie à partir d'un polymère d'au moins 3 monomères de sucres, d'acides aminés, de glycols, d'alcools, de lipides ou de phospholipides.

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