Virus vector for introducing gene into renal cells

Details Virus vector for introducing gene into renal cells Virus vector for introducing gene into renal cells

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 35/76 (2006.01) C12N 7/00 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2414077

A virus vector whereby a gene can be transferred into renal cells at a high efficiency. Use of a paramyxovirus vector makes it possible to transfer a gene into renal cells at a high efficiency. The gene transferred by the in vivo administration can be continuously expressed in the renal cells over a prolonged period of time. This vector is adequately usable in gene therapy for kidney.

L'invention concerne un vecteur de virus pour le transfert de gène dans des cellules rénales, avec une efficacité élevée. L'utilisation d'un vecteur de paramyxovirus permet d'assurer ce transfert. L'expression du gène transféré par administration <i>in vivo</i> est continue dans lesdites cellules, sur une période prolongée. Le vecteur convient à la thérapie génique pour les reins

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