Vitamin d analogues and their neuronal effects

A - Human Necessities – 61 – K

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A61K 31/59 (2006.01)

Patent

CA 2290772

The present invention is directed, inter alia, to methods of utilizing low calcemic vitamin D analogues. Particularly, the present invention is directed to using low calcemic vitamin D analogues to treat neurodegenerative diseases and disorders, to facilitate endogenous production of neurotrophic factors, to inhibit the degradation, dysfunction or loss of neural cells and/or to enhance the phenotype of neural cells or neuronal processes.

La présente invention a trait, entre autres, à des procédés d'utilisation d'analogues de vitamine D à faible teneur en calcium. En particulier, la présente invention a trait à l'utilisation d'analogues de vitamine D à faible teneur en calcium pour traiter des maladies et des troubles neurodégénératifs, pour faciliter la production endogène de facteurs neurotrophiques, pour inhiber la dégradation, le dysfonctionnement ou la perte de cellules nerveuses et/ou améliorer le phénotype de cellules nerveuses ou de processus neuronaux.

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