Vitamin d analogues and their pharmaceutical use

Details Vitamin d analogues and their pharmaceutical use Vitamin d analogues and their pharmaceutical use

C - Chemistry, Metallurgy

07

C

C07C 401/00 (2006.01) A61K 31/59 (2006.01) A61P 17/00 (2006.01) A61P 19/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2371165

The present invention relates to compounds of general formula (I) wherein R1 and R2, which may be the same or different, represent (C1-C4)alkyl, and R3 represents hydrogen, halogen, (C1-C4)alkyl, or O-(C1-C4)alkyl, and in-vivo hydrolysable esters thereof with pharmaceutically acceptable acids. The present compounds are of value in the human and veterinary practice.

La présente invention concerne des composés représentés par la formule générale (I). Dans cette formule R?1¿ et R?2¿, qui peuvent être semblables ou différents, représentent (C¿1?-C¿4?)alkyle, et R?3¿ représente hydrogène, halogène, (C¿1?-C¿4?)alkyle, ou O-(C¿1?-C¿4?)alkyle, et des esters hydrolysables in-vivo de ceux-ci avec des acides pharmaceutiquement acceptables. Ces composés sont utiles pour la médecine des hommes et pour les activités vétérinaires.

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