Vitamin d compounds and method of preparing these compounds

Details Vitamin d compounds and method of preparing these compounds Vitamin d compounds and method of preparing these compounds

C - Chemistry, Metallurgy

07

C

C07C 401/00 (2006.01) A61K 31/59 (2006.01) A61K 49/00 (2006.01) C07C 49/513 (2006.01) C07D 303/14 (2006.01) A61K 7/48 (2000.01)

Patent

CA 2097997

The invention relates to a new vitamin D compound of the general formula Image wherein: R1 is a hydrogen atom or a hydroxy group; R2 is a (C1-C3)alkyl group, a hydroxy(C1-C3)alkyl group, a (C1-C2) alkoxymethyl group or a (C2-C3) alkenyl or alkynyl group; R3 is a branched or non-branched, saturated or unsaturated aliphatic 3- to 5-membered hydrocarbon or oxahydrocarbon biradical, having at least 3 atoms in the main chain and being optionally substituted with one or more substituents selected from epoxy, fluoro and hydroxy; R4 is a sec. or tert. (C3-C6)alkyl group or a (C3-C6)cycloalkyl group; and A and B are each individually hydrogen atoms or methyl groups, or A and B form together a methylene group. The invention further relates to a method of preparing these compounds and to their use in pharmacotherapy and cosmetics.

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