Vitamin d compounds and method of preparing these compounds

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 401/00 (2006.01) A61K 31/59 (2006.01) C07D 303/14 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2164916

The present invention relates to vitamin D compounds of the general formula Image (I) wherein: R1 is a hydrogen atom or a hydroxy group; R2 is a (C1-C3)alkyl group, a hydroxy(C1-C3)alkyl group, a (C1-C2)alkoxymethyl group or a (C2-C3)alkenyl or alkynyl group; n is 0 or 1; R3 is a branced or non-branched, saturated or unsaturated, substituted or unsubstituted aliphatic (C3-C7)hydrocarbon or oxahydrocarbon biradical; R3 is a branched or straight (C1-C6)alkyl group or a (C3-C6)cycloalkyl group; and A and B are each individually hydrogen atoms or methyl groups, or A and B form together a methylene group. The present compounds find use in cosmetic application and in human and veterinary pharmacotherapeutic practice in the treatment of skin and bone diseases, diseases related to cell differentiation/cell proliferation, imbalance in the immune system and inflammatory diseases.

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