C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/77 (2006.01) A61K 31/12 (2006.01) C07D 405/12 (2006.01) C07D 407/10 (2006.01) C07D 407/12 (2006.01)
Patent
CA 2544857
The present invention relates to novel, non-secosteroidal, phenyl-benzofuran compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1.alpha.,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.
La présente invention a trait à de nouveaux composés de phényl-benzofurane non sécostéroïdes avec une activité modulatrice de récepteur de la vitamine D qui sont moins hypercalcémiques que la vitamine D3 1.alpha.,25 dihydroxy. Ces composés sont utiles pour le traitement de maladie osseuse et de psoriasis.
Lu Jianliang
Ma Tianwei
Nagpal Sunil
Ochoada Jason Matthew
Shen Quanrong
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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