Vitamin d receptor modulators

Details Vitamin d receptor modulators Vitamin d receptor modulators

C - Chemistry, Metallurgy

07

C

C07C 59/90 (2006.01) A61K 31/12 (2006.01) A61K 31/165 (2006.01) A61K 31/18 (2006.01) A61K 31/19 (2006.01) A61K 31/192 (2006.01) A61K 31/235 (2006.01) A61K 31/41 (2006.01) A61K 31/426 (2006.01) C07C 59/48 (2006.01) C07C 59/64 (2006.01) C07C 59/66 (2006.01) C07C 62/24 (2006.01) C07C 65/24 (2006.01) C07C 65/34 (2006.01) C07C 65/40 (2006.01) C07C 69/732 (2006.01) C07C 69/734 (2006.01) C07C 69/738 (2006.01) C07C 69/76 (2006.01) C07C 69/78 (2006.01) C07C 69/94 (2006.01) C07C 235/34 (2006.01) C07C 235/42 (2006.01)

Patent

CA 2506891

The present invention relates to novel, non-secosteroidal, diaryl compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1a,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.

L'invention concerne de nouveaux composés diaryle à liaison carbone non sécostéroïdale à activité modulatrice du récepteur de vitamine D (VDR) qui sont moins hypercalcémique que la vitamine D3 de 1.alpha.,25 dihydroxy. Ces composés sont utiles dans le traitement de maladies osseuses et du psoriasis.

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