C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 311/08 (2006.01) A61K 31/18 (2006.01) A61K 31/255 (2006.01) A61P 19/08 (2006.01) A61P 19/10 (2006.01) C07C 309/65 (2006.01) C07C 309/66 (2006.01) C07C 311/09 (2006.01)
Patent
CA 2544517
The present invention relates to novel, non-secosteroidal, sulfonate and sulfonamide functional diaryl compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1.alpha.,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis. X-15439
L'invention concerne des composés fonctionnels diaryle non secostéroïdaux de sulfonate et de sulfonamide possédant une activité de modulation du récepteur de la vitamine D (VDR), lesquels sont moins hypercalcémiques que la 1?,25 dihydroxy vitamine D3. Les composés selon l'invention sont utiles dans le traitement de maladies osseuses et du psoriasis.
Gajewski Robert Peter
Jones Charles David
Linebarger Jared Harris
Lu Jianliang
Ma Tianwei
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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