C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 401/00 (2006.01) A61K 31/59 (2006.01)
Patent
CA 2205275
Compounds of the formula (see Formula I) wherein R is hydrogen, fluorine, or hydroxy, R2 is hydrogen, lower alkyl or halogen, X is =CH2 or when R is hydroxy, X is (H,H) or =CH2, and A is -C .ident. C- , (see Formula II), (see Formula III) or -CH2-CH2-, are useful in the treatment of hyperproliferative skin disorders, neoplastic diseases, sebaceous gland diseases, and conditions associated with photodamaged skin.
Batcho Andrew David
Bryce Graeme Findlay
Hennessy Bernard Michael
Iacobelli Jerome Anthony
Uskokovic Milan Radoje
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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