C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 401/00 (2006.01) A61K 31/59 (2006.01) A61P 3/02 (2006.01) A61P 3/14 (2006.01) A61P 11/00 (2006.01) C07F 7/18 (2006.01)
Patent
CA 2348235
Compounds represented by general formula (1), wherein R01 and R02 are each independently hydrogen or a hydroxyl-protecting group; and Z is a group represented by general formula (1-1), (1-2), (1-3), (1-4) or (1-5). These compounds are useful as active ingredients of the remedies for inflammatory respiratory diseases, malignant tumor, articular rheumatism, osteoporosis, true diabetes, hypertension, alopecia, acne, psoriasis, dermatitis, hypercalcemia, hypofunction of accessory thyroid, or metabolic disorder of cartilage.
Composés représentés par la formule (1) dans laquelle R¿01? et R¿02? représentent chacun indépendamment hydrogène ou un groupe protecteur hydroxyle; Z représente un groupe illustré par la formule (1-1), (1-2), (1-3), (1-4) ou (1-5). Ces composés sont utiles en tant qu'ingrédients actifs de médicaments contre des maladies respiratoires inflammatoires, des tumeurs malignes, des rhumatismes articulaires, l'ostéoporose, le diabète sucré, l'hypertension, l'alopécie, l'acné, le psoriasis, la dermatite, l'hypercalcémie, le dysfonctionnement thyroïdien ou les troubles métaboliques du cartilage.
Gao Qingzhi
Ishizuka Seiichi
Manabe Kenji
Sogawa Ryo
Takano Yasuhiro
Borden Ladner Gervais Llp
Teijin Limited
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