C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
204/91.05, 260/6
C07C 401/00 (2006.01) C07J 9/00 (2006.01) C07J 41/00 (2006.01) C07J 71/00 (2006.01)
Patent
CA 1330806
ABSTRACT 1.alpha.-hydroxy vitamin D3 derivatives of the formula: Image where R1 is a hydroxyl group, an amino group or the group OR' (where R' is a lower alkyl group having 1 to 7 carbon atoms that may or may not be substituted by a hydroxyl group, a halogen atom, a cyano group, a lower alkoxy group having 1 to 3 carbon atoms, an amino group, or an acylamino group); R2 is a hydrogen atom or a hydroxyl group, and a process for preparing the same are disclosed. The compounds represented by the formula above have a calcium control action and the ability to induce differentiation in tumor cells and, therefore, are useful as an antitumor agents and a medicine for treating calcium dysbolism-caused diseases.
496985
Kubodera Noboru
Matsunaga Isao
Miyamoto Katsuhito
Murayama Eigoro
Ochi Kiyoshige
Chugai Seiyaku Kabushiki Kaisha
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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