Vitamin e succinate stabilized pharmaceutical compositions,...

A - Human Necessities – 61 – K

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A61K 9/10 (2006.01) A61K 9/00 (2006.01) A61K 9/107 (2006.01) A61K 9/127 (2006.01) A61K 9/19 (2006.01) A61K 31/337 (2006.01) A61K 31/355 (2006.01) A61K 47/14 (2006.01)

Patent

CA 2641146

The present invention provides vitamin E succinate (VES)-stabilized compositions, methods for the preparation thereof and methods useful for the in vivo delivery of substantially water insoluble and optionally chemically unstable pharmacologically active agents (such as docetaxel).

La présente invention concerne des compositions stabilisées par un succinate de vitamine E (VES), des procédés de préparation de celles-ci et des procédés utiles à l'administration in vivo d'agents pharmacologiquement actifs en grande partie insolubles dans l'eau et parfois chimiquement instables (tels que le docétaxel).

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