Vitreous form of known bradykinin antagonist

Details Vitreous form of known bradykinin antagonist Vitreous form of known bradykinin antagonist

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4709 (2006.01)

Patent

CA 2347001

This invention relates to a vitreous form of 8-[3-[N-[(E)-3-(6- acetamidopyridin-3-yl) acryloylglycyl]-N-methylamino]-2,6-dichlorobenzyloxy]-2- methylquinoline (FR173657) of formula (I). This vitreous form has good solid stability and, therefore, is useful for producing and supplying FR173657 products whose quality is stable enough to be suitable for medicines.

L'invention a trait à une forme vitreuse de 8-[3-[N-[(E)-3-(6-acétamidopyridine-3-yl) acryloylglycyl]-N-méthylamino]-2,6-dichlorobenzyloxy]-2-méthylquinoline (FR173657) représentée par la formule (I). Cette forme vitreuse présente une bonne stabilité de solide, et, de ce fait, est utile pour produire et fournir des produits de FR173657 assez stables pour être utilisés comme médicaments.

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