C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/55 (2006.01) A61K 31/675 (2006.01) C07D 217/24 (2006.01) C07D 235/16 (2006.01) C07D 243/14 (2006.01) C07D 401/00 (2006.01) C07D 403/00 (2006.01) C07D 405/00 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07D 471/04 (2006.01) C07D 519/00 (2006.01) C07F 9/547 (2006.01)
Patent
CA 2225273
Vitronectin receptor antagonists, their preparation and their use The present invention relates to compounds of the formula I A-B-D-E-F-G (I) in which A, B, D, E, F and G have the meanings given in the patent claims, to their preparation and to their use as medicaments. The compounds of the invention are used as vitronectin receptor antagonists and as inhibitors of bone resorption.
Antagonistes du récepteur de la vitronectine, leur préparation et leur utilisation. L'invention concerne les composés de la formule 1, A-B-D-E-F-G(I), dans laquelle A, B, D, E, F et G ont la signification donnée dans les revendications du brevet, de même que leur préparation et leur utilisation comme médicaments. Les composés décrits sont utilisés comme antagonistes du récepteur de la vitronectine et comme inhibiteurs de la résorption osseuse.
Carniato Denis
Gadek Thomas Richard
Knolle Jochen
Lefrancois Jean-Michel
Mcdowell Robert
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Genentech Inc.
Hoechst Aktiengesellschaft
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