Volatile active substance containing plaster that may be...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/70 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2172402

An active substance-containing plaster with a pressure sensitive fixing device, containing at least one readily volatile ingredient, consisting of a substantially active substance-impermeable backing layer, at least two active substance-containing matrix layers and a removable protective layer, whereby the matrix layer containing the readily volatile active substance is laminated on a separately produced composite of one or more further matrix layers which are active substance-free, is characterized in that the first active substance-containing matrix layer consists of a spreadable molecularly disperse solution of the matrix base material in the readily volatile ingredient as the exclusive solvent, the composite which is obtained after laminating forming an active substance matrix that is as a whole shear-resistant after migration of the readily volatile ingredient into the composite.

Un pansement contenant des principes actifs et pourvu d'un agencement de fixation auto-adhésif contient au moins un ingrédient très volatil et est constitué d'une couche de fond sensiblement imperméable au principe actif, d'au moins deux couches matricielles qui contiennent le principe actif et d'une couche détachable de protection. La couche matricielle qui contient le principe actif très volatil est appliquée sur un composite produit séparément d'une ou plusieurs couches matricielles supplémentaires exemptes de principe actif. Le pansement contenant des principes actifs se caractérise en ce que la première couche matricielle, celle qui contient le principe actif, est constituée d'une solution moléculaire étalable du matériau de base de la matrice dispersée dans l'ingrédient très volatil comme seul solvant. Le composite obtenu après application des couches forme après migration de l'ingrédient très volatile une matrice contenant le principe actif qui dans son ensemble est très résistante au cisaillement.

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