A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/16 (2006.01) A61K 35/76 (2006.01) A61P 17/06 (2006.01) A61P 35/00 (2006.01) C07K 14/16 (2006.01) C12N 15/49 (2006.01) C12Q 1/70 (2006.01)
Patent
CA 2155017
Pharmaceutical compositions comprising the HIV protein vpr or nucleic acid molecule encoding vpr are disclosed. Also disclosed are methods of treating patients suffering from diseases characterized by hyperproliferating undifferentiated cells such as cancer by administering such compositions. Methods of identifying compounds which have anti-HIV activity are disclosed, in particular, methods of identifying compounds which modulate the activity of vpr and of identifying compounds which inhibit vpr binding to the HIV protein gag.
Levy David Nathan
Refaeli Yosef
Weiner David B.
Levy David Nathan
Refaeli Yosef
Smart & Biggar
Weiner David B.
LandOfFree
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