C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) C07H 21/02 (2006.01) C12N 9/22 (2006.01)
Patent
CA 2208097
Ribozyme able to cleave a separate substrate RNA molecule, said ribozyme having three base-paired regions generally, but not limited to, in a proposed "I" configuration, wherein "upper" and "lower" based-paired regions comprise between about 4 and 80 bases inclusive of which at least about 50 % are paired with each other, and wherein the "connecting" region between said upper and lower base paired regions comprises between about 4 and 20 bases inclusive of which at least about 50 % are paired.
Ribozyme capable de couper une molécule séparée d'ARN substrat, ladite ribozyme ayant généralement trois régions à paires de bases, mais n'étant pas limitée à ces trois régions, dans une configuration proposée en "I" dans laquelle les régions à paires de bases "supérieure" et "inférieure" comprennent entre environ 4 et 80 bases dont au moins environ 50 % sont appariées les unes avec les autres, et dans laquelle la région de liaison entre lesdites régions à paires de bases supérieure et inférieure comporte entre environ 4 et 20 bases dont au moins environ 50 % sont appariées.
Collins Richard
Smart & Biggar
LandOfFree
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