W-amino-loweralkanoylamido derivatives of hexahydro...

Details W-amino-loweralkanoylamido derivatives of hexahydro... W-amino-loweralkanoylamido derivatives of hexahydro...

C - Chemistry, Metallurgy

07

D

260/279.3, 260/3

C07D 407/12 (2006.01) C07D 295/14 (2006.01) C07D 307/91 (2006.01)

Patent

CA 1040632

ABSTRACT OF THE DISCLOSURE: The invention has as object a process for preparing new derivatives of hexahydrodibenzofuran-3-one and their pharma- ceutically acceptable nontoxic addition salts with acids. This Process consists in reacting 8, 9b-dimethyl 1,2,3,4,4a, 9b-hexahy- dro-4-aminodibenzofuran-3-one with an acyl halide to give an intermediare, which is further reacted with an non-tertiary amine. The so-obtained derivatives possess an antitussive acti- vity.

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