Wasp family protein fragments, and use therof

Details Wasp family protein fragments, and use therof Wasp family protein fragments, and use therof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/37 (2006.01) C07K 14/39 (2006.01) C07K 14/395 (2006.01) C07K 14/47 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2393834

The invention concerns peptide fragments of the WASP family proteins, or peptides derived from said fragments, and their uses in particular for preparing reagents for use in implementing a method for detecting or screening molecules with inhibiting or stimulating effect on the formation of the actin cytoskeleton, hence an inhibiting or stimulating effect on cellular motility.

La présente invention a pour objet des fragments peptidiques de protéines de la famille WASP, ou les peptides dérivés de ces fragments, ainsi que leurs utilisations notamment pour la préparation de réactifs utilisables dans le cadre de la mise en oeuvre d'un procédé de détection ou de criblage de molécules ayant un effet d'inhibition ou de stimulation de la formation du cytosquelette d'actine, et donc un effet d'inhibition ou de stimulation de la motilité cellulaire.

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