Water and solvent soluble axial hydroxy and mono- and...

Details Water and solvent soluble axial hydroxy and mono- and... Water and solvent soluble axial hydroxy and mono- and...

C - Chemistry, Metallurgy

07

F

167/119, 260/383

C07F 15/00 (2006.01) A61K 31/28 (2006.01) A61K 31/555 (2006.01)

Patent

CA 2027792

A B S T R A C T This invention relates to axial hydroxy or axial mono- or di- carboxylate platinum (IV) derivatives which possess antitumor activity, a method for therapeutically treating an animal host affected by a malignant tumor which comprises administering to said host an effective tumor-inhibiting dose of a compound according to the invention, and pharmaceutical compositions which comprise a pharmaceutically effective amount of a compound according to the invention in combination with an inert pharmaceutically acceptable carrier or diluent.

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