Water insoluble derivatives of hyaluronic acid

Details Water insoluble derivatives of hyaluronic acid Water insoluble derivatives of hyaluronic acid

C - Chemistry, Metallurgy

08

B

167/168, 260/219

C08B 37/08 (2006.01) A61K 47/26 (2006.01) A61K 47/36 (2006.01) A61L 27/20 (2006.01) A61L 27/52 (2006.01) A61L 31/04 (2006.01) A61L 31/14 (2006.01) A61L 31/16 (2006.01)

Patent

CA 1332235

Abstract of the Disclosure A method for making a water insoluble biocompatible gel includes activating HA with an activating agent to form activated HA, and reacting the activated HA with a nucleophile, under conditions producing the water insoluble biocompatible gel. Also, a method for making a water insoluble biocompatible film includes providing a biocompatible gel made according to the above method, and drying the gel or compressing the gel under conditions permitting escape of water from the gel. Also, a water insoluble composition including HA is prepared without the use of any bifunctional or polyfunctional nucleophile.

577623

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